If TI equals 10, what is the relationship between TD50 and ED50?

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Multiple Choice

If TI equals 10, what is the relationship between TD50 and ED50?

Explanation:
Therapeutic index is the ratio of the toxic dose that affects 50% of the population to the effective dose that produces the desired effect in 50% of the population. In symbols, TI = TD50 / ED50. If TI equals 10, then TD50 = 10 × ED50. That means the dose causing toxicity at 50% of people is ten times higher than the dose that achieves the desired therapeutic effect, indicating a relatively wide safety margin.

Therapeutic index is the ratio of the toxic dose that affects 50% of the population to the effective dose that produces the desired effect in 50% of the population. In symbols, TI = TD50 / ED50. If TI equals 10, then TD50 = 10 × ED50. That means the dose causing toxicity at 50% of people is ten times higher than the dose that achieves the desired therapeutic effect, indicating a relatively wide safety margin.

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